DHEAS is the sulfated form of DHEA, and it circulates in the bloodstream in higher concentrations than DHEA. The DHEAS test is commonly used to assess adrenal gland function, especially in diagnosing disorders related to excess androgen production like adrenal tumors or congenital adrenal hyperplasia.

Clinical Applications:

Adrenal disorders: High DHEAS levels can indicate adrenal hyperplasia or adrenal tumors, both of which affect hormone production.

Evaluating hirsutism or virilization: DHEAS levels are used to investigate conditions that cause excessive hair growth or masculinization in women.

Menopause and aging: DHEAS decreases with age and may be monitored in aging individuals to assess age-related health changes.